Table of Contents
What is the difference between LDL-C and LDL-P?
LDL-P is often used to get a more accurate measure of LDL due to the variability of cholesterol content within a given LDL. Studies have shown that LDL-P more accurately predicts risk of cardiovascular disease than LDL-C.
What does sdLDL C mean?
Small, dense low-density lipoprotein cholesterol (sdLDL-c), a type of smaller LDL-c, is considered an emerging risk factor for T2DM and CVD.
What does high LDL-P mean?
LDL-P. • LDL-P is the direct measure of low density lipoprotein particles – the causal link between high levels of LDL-P and development of cardiovascular disease (CVD) is well established. • Studies have demonstrated per-particle cholesterol amount. varies in patients with type II diabetes, statin-treated.
What causes sdLDL?
(For those interested, part of the explanation for the atherogenicity of sdLDL-C is due to their reduced systemic clearance by the LDL receptor; their increased vulnerability to oxidation; they are retained preferentially by artery walls; and they carry lipoprotein-associated phopholipase, which has an important role …
How do I lower my LDL-P Small?
Methods for lowering LDL-P levels include more aggressive lifestyle changes (diet, exercise and weight loss), niacin, fibrates and fish oil. U.S. Food and Drug Administration-approved fish oils (Lovaza or Vascepa, a new EPA fish oil) at 4 grams per day lower LDL-P by about 10 percent.
What is the difference between HDL C and HDL P?
High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an established atheroprotective marker, in particular for coronary artery disease; however, HDL particle concentration (HDL-P) may better predict risk.
What are the subclasses of LDL?
There are three major subclasses of LDL with distinct densities: n-LDL subclass A contains more of the larger and less dense LDL particles (density of 1.025–1.034 g/mL); an intermediate group, n-LDL subclass I has density of 1.034–1.044 g/mL; and finally, n-LDL subclass B, which has more smaller and denser LDL …
What is a good LDL particle size?
For LDL particle size, we classified patients from 18.0 to 21.2 as phenotype B and patients from 21.3 to 23.0 as phenotype A (4). For LDL-P, we categorized patients as optimal (<1,100), near optimal (1,101–1,399), borderline-high (1,400–1,799), high (1,800–2,100) or very high (>2,100).
How do I lower my LDL-P levels?
Do Statins lower LDL-P?
Although statins lower LDL-P, they may leave a significant number of patients above the LDL-P target. Patients with high levels of triglycerides and low HDL-C are likely to have high LDL-P despite normal or low LDL-C. Such a lipid profile is typical for individuals with metabolic syndrome.
Is sdLDL the same as VLDL?
The main difference between VLDL and LDL is that they have different percentages of the cholesterol, protein, and triglycerides that make up each lipoprotein. VLDL contains more triglycerides. LDL contains more cholesterol. VLDL and LDL are both considered types of “bad” cholesterol.
How do I lower my LDL P Small?
Can I reduce my amount of small, dense LDLs?
- Eat a diet very rich in soluble fiber (BYOBB) – Beans, Yams, Oats, Barley, and Berries.
- Eat fewer refined carbohydrates.
- Eat much less saturated and trans fats and cholesterol.
- Exercise regularly, and.
- Lose excess weight.