Table of Contents
What is the difference between synthase and synthetase?
Synthase is any enzyme that catalyses the synthesis of a biological compound but, unlike synthetases, does not make use of ATP as a source of energy while synthetase is any ligase that synthesises biological compounds using ATP as a source of energy.
What is the function of ATP synthase synthetase )?
The function of ATP synthase is to synthesize ATP from ADP and inorganic phosphate (Pi) in the F1 sector. This is possible due to energy derived from a gradient of protons which cross the inner mitochondrial membrane from the intermembrane space into the matrix through the Fo portion of the enzyme.
What is the relationship between ATP synthase and ATP?
The ATP synthase is a mitochondrial enzyme localized in the inner membrane, where it catalyzes the synthesis of ATP from ADP and phosphate, driven by a flux of protons across a gradient generated by electron transfer from the proton chemically positive to the negative side.
What is ATP synthase also known as?
The present article concerns the ATP synthase (also known as the F-ATPase or F1Fo-ATPase), which, although not studied by Keilin himself, is one of the main beneficiaries of the electron-transfer processes in mitochondria, bacteria and chloroplasts, and is a key enzyme in energy conversion in biology.
Does synthetase use ATP?
ATP synthetase (ATP synthase; F 0F 1 complex) An enzyme complex that catalyses the formation of ATP from ADP and inorganic phosphate. The synthetase complex consists of a membrane-spanning proton channel (the F 0 portion) and an ATP-synthesizing part (the F 1 portion). …
What is the meaning of synthetase?
Definition of synthetase : an enzyme that catalyzes the linking together of two molecules usually using the energy derived from the concurrent splitting off of a pyrophosphate group from a triphosphate (such as ATP) — called also ligase.
What is the main difference between the molecule ADP and ATP?
ATP is adenosine triphosphate and contains three terminal phosphate groups, whereas ADP is adenosine diphosphate and contains only two phosphate groups. ADP is produced on hydrolysis of ATP and the energy released in the process is utilised to carry out various cellular processes.
Where is glutamine synthetase found?
GS is present predominantly in the brain, kidneys, and liver. GS in the brain participates in the metabolic regulation of glutamate, the detoxification of brain ammonia, the assimilation of ammonia, recyclization of neurotransmitters, and termination of neurotransmitter signals.