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Is 1000 mg too much for B12?
In one 8-week study in 100 older adults, supplementing with 500 mcg of vitamin B12 were found to normalize B12 levels in 90\% of participants. Higher doses of up to 1,000 mcg (1 mg) may be necessary for some ( 10 ).
What happens if to much B12 is too high?
However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.
Is 1000 mcg of B12 safe for seniors?
Recommended Vitamin B12 Dosage for Seniors The proper vitamin B12 dosage for seniors depends on if they have underlying health conditions and how severe their deficiency is. In some cases, doctors may recommend high doses — more than 1,000 micrograms (mcg) per day.
What causes too much B12 in the blood?
The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.
Is 1100 B12 level too high?
The normal range for vitamin B12 (total) is between 200 – 1100 ng/L (nanograms per liter), 200 – 1100 pg/mL (picograms per milliliter), or 148 – 811 pmol/L (picomoles per liter). The normal range for active vitamin B12 (holoTC) is around 20 – 134 pmol/L (picomoles per liter).
Are there any side effects of taking too much vitamin B12?
Safety and side effects. When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.
Is it safe to take vitamin B12 supplements?
Vitamin B12 is an essential nutrient, important in nerve and blood cell health, and most people obtain enough of it in food. Those with B12 deficiency, or an inability to absorb it, can use supplements. But a study in JAMA Network Open suggests that very high blood levels of vitamin B12 may be life-threatening.
What is the main cause of vitamin B12 deficiency?
The main causes of vitamin B12 deficiency include vitamin B12 malabsorption from food, pernicious anemia, postsurgical malabsorption, and dietary deficiency [12]. However, in many cases, the cause of vitamin B12 deficiency is unknown.
What is the normal range of vitamin B12 in blood?
Vitamin B12 status is typically assessed via serum or plasma vitamin B12 levels. Values below approximately 170–250 pg/mL (120–180 picomol/L) for adults [5] indicate a vitamin B12 deficiency.