How accurate is Alere Determine?
The sensitivity for detecting HIV infection among the panel samples was 95\% (95\%CI 88–98\%) for the Alere Determine HIV-1/2 Combo and for the SD Combo 91\% (95\%CI 83–96\%). Both assays showed an overall specificity of 100\% (95\%CI 90–100\%).
How early can Alere Determine detect HIV?
Timeframe for Alere Determine™ HIV-1/2 Ag/Ab Combo ONLY: Antigen can be detected 14-15 days after infection (Acute Infection). Antigen and antibodies can both be detected 21-28 days after infection (Early Infection).
How accurate is HIV 1 and 2 antibody?
The results of both tests together are more than 99\% accurate. The tests used to confirm HIV infection are either the Western blot or indirect fluorescent antibody (IFA) test. If your screening test went to a laboratory, they can do this additional testing on the same blood sample.
Can the Alere determine HIV test detect p24 antigen?
Most rapid tests, with the exception of the Alere HIV Combo and Alere Determine HIV-1/2 cannot detect p24 antigen. The accuracy of point-of-care tests is not always equal to those of laboratory tests, especially in relation to recent infection. This is for two main reasons:
How accurate is the first response HIV card test?
The specificities of the First Response HIV Card Test 1–2.0, INSTI HIV-1/HIV-2 Antibody Test, Determine HIV-1/2 and Genie Fast HIV 1/2 were all between 90 and 95\%. The findings confirm that the diagnosis of HIV should not be based on results from a single HIV rapid diagnostic test.
How long do antibody tests take to detect HIV?
Antibody tests can take 23 to 90 days to detect HIV infection after an exposure. Most rapid tests and self-tests are antibody tests. In general, antibody tests that use blood from a vein can detect HIV sooner after infection than tests done with blood from a finger prick or with oral fluid.
What is Alere determine HIV–1/2 AG/AB combo?
Indications: Alere Determine HIV–1/2 Ag/Ab Combo is an in vitro, visually read, rapid qualitative immunoassay for the simultaneous detection of HIV-1 p24 antigen and antibodies to both HIV-1 and HIV-2 in human serum, plasma, capillary (fingerstick) whole blood or venipuncture (venous) whole blood.