What if SGOT is higher than SGPT?
An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70\% of these patients compared with 26\% of patients with postnecrotic cirrhosis, 8\% with chronic hepatitis, 4\% with viral hepatitis and none with obstructive jaundice.
Does high SGPT mean jaundice?
SGPT activity persists longer than the SGOT. This enzyme is raised before there are clinical findings of jaundice. In viral hepatitis, the SGPT/SGOT ratio is greater than 1. Other than the viral cause, the SGPT/SGOT ratio is less than 1.
What are the normal levels of SGOT and SGPT?
What Are Normal Levels of SGOT and SGPT? The normal levels of SGOT is in between 5 and 40 units per liter of serum and the normal levels of SGPT in between 7 and 56 units per liter of serum. The normal ranges of SGOT and SGPT may slightly differ depending on the protocols and techniques used to measure them by different laboratories.
Are sgsgot and SGPT a good marker of liver damage?
SGOT and SGPT are highly sensitive markers of liver damage due to various diseases or injury. However, the fact is that higher than normal levels should not be automatically considered as indicative of liver damage.
What is the difference between SGPT and AST levels?
For instance, blood AST level is increased in conditions of muscle injury and heart attacks. Hence, it is not highly specific liver tissue damage indicator as it can be elevated in conditions other than liver damage. By contrast, SGPT is normally present in large concentrations in the liver.
How does hepatitis C affect SGOT and SGPT levels?
Conversely, individuals developing chronic hepatitis C infection have minor elevations in their SGOT and SGPT levels, whereas, their liver is injured or damaged substantially by the infection even leading to scarring (cirrhosis) from ongoing liver infection and inflammation.