What is the difference between benzathine penicillin and penicillin G?

What is the difference between benzathine penicillin and penicillin G?

Penicillin G benzathine intramuscular injections are primarily used to treat Treponema infections and to eradicate colonization of group A β-hemolytic streptococci in chronic carriers. Benzathine is the least soluble salt form of penicillin G, thus providing the longest duration of action (up to 3 weeks).

What is the difference between benzylpenicillin and procaine penicillin?

Procaine penicillin G is a combination of benzylpenicillin with the local anaesthetic agent procaine. It is slowly absorbed after IM administration and hydrolysed to benzylpenicillin and thus used to achieve prolonged but low concentrations of benzylpenicillin.

Is benzathine penicillin the same as procaine penicillin?

Bicillin C-R 900/300 (penicillin G benzathine and penicillin G procaine injectable suspension) contains the equivalent of 900,000 units of penicillin G as the benzathine and 300,000 units of penicillin G as the procaine salts. It is available for deep intramuscular injection.

What is the point of the benzathine in benzathine penicillin?

Penicillin G benzathine and penicillin G procaine injection is in a class of medications called penicillins. It works by killing bacteria that cause infections.

Why is penicillin G and procaine combined?

The procaine component is an amino ester local anesthetic acting on the fast sodium channel to produce local anesthesia. The intent of this anesthetic addition is primarily to ease the pain of IM injection in large enough doses to reach therapeutic concentrations of penicillin.

Why is penicillin combined with procaine?

This drug is used where prolonged exposure to benzylpenicillin at a low concentration is required. This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin.

How does benzathine penicillin G work?

Penicillin G benzathine injection is in a class of antibiotics called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G benzathine injection will not work for colds, flu, or other viral infections.

Why is procaine used in the process of production of penicillin?

What is the molecular formula of procaine?

C13H20N2O2Procaine / Formula

Why probenecid is used along with penicillin?

Probenecid is sometimes used along with penicillin antibiotics (e.g., penicillin, ampicillin, nafcillin) to increase antibiotic blood levels. This increase makes the antibiotic work better at treating certain infections. Probenecid works by decreasing the kidneys’ ability to remove the antibiotic from the body.

What is the work of procaine penicillin?

Procaine penicillin is an antibiotic that fights bacteria in your body. Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually transmitted disease). Do not use this medication for any other infection that has not been checked by your doctor.

Can procaine penicillin cure gonorrhea?

Penicillin G procaine injection is used to treat certain infections caused by bacteria. Penicillin G procaine injection should not be used to treat gonorrhea (a sexually transmitted disease) or early in the treatment of certain serious infections.

What are the side effects of penicillin G?

Your health care provider can discuss with you a more complete list of side effects. Some possible uncommon but serious side effects of penicillin G procaine include: A life-threatening allergic reaction (symptoms are difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives)

How to administer penicillin G?

Penicillin G procaine (aqueous) is for intramuscular injection only. Administer by DEEP INTRAMUSCULAR INJECTION in the upper, outer quadrant of the buttock. In neonates, infants and small children, the midlateral aspect of the thigh may be preferable. When doses are repeated, vary the injection site.

What is the difference between penicillin G and V?

Its just a chemistry thing. Penicillin v is an analog of penicillin g. Penicillin v is more resistant to the effects of stomach acid on it. They are both penicillin and they both do the same thing as far as infections.

What does penicillin G MEAN?

Penicillin G is bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. It acts by inhibiting biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci.